Gene F Coppa Selected Research

Acute Lung Injury

1/2023	An engineered miRNA PS-OMe miR130 inhibits acute lung injury by targeting eCIRP in sepsis.
1/2020	An extracellular cold-inducible RNA-binding protein-derived small peptide targeting triggering receptor expressed on myeloid cells-1 attenuates hemorrhagic shock.
7/2015	Stimulation of Brain AMP-Activated Protein Kinase Attenuates Inflammation and Acute Lung Injury in Sepsis.
3/2015	AICAR attenuates organ injury and inflammatory response after intestinal ischemia and reperfusion.
12/2013	Growth arrest-specific protein 6 attenuates neutrophil migration and acute lung injury in sepsis.

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Gene F Coppa Research Topics

Disease

24	Inflammation (Inflammations) 01/2023 - 04/2012
22	Sepsis (Septicemia) 01/2023 - 11/2009
19	Ischemia 01/2023 - 09/2010
15	Body Weight (Weight, Body) 01/2022 - 09/2012
9	Reperfusion Injury 12/2018 - 09/2010
8	Hemorrhagic Shock 01/2020 - 03/2012
8	Hemorrhage 02/2016 - 01/2009
6	Lung Injury 09/2018 - 02/2016
5	Acute Lung Injury 01/2023 - 12/2013
5	Wounds and Injuries (Trauma) 08/2021 - 09/2010
4	Necrosis 09/2018 - 01/2011
4	Neonatal Sepsis 09/2018 - 01/2017
3	Shock 02/2016 - 03/2015
2	Pneumonia (Pneumonitis) 01/2022 - 04/2018
2	Acute Kidney Injury (Acute Renal Failure) 01/2017 - 01/2012
2	Neoplasms (Cancer) 02/2016 - 09/2012
2	Delayed Graft Function 03/2015 - 07/2014
2	Traumatic Brain Injuries (Traumatic Brain Injury) 07/2014 - 03/2012
2	Brain Injuries (Brain Injury) 07/2014 - 03/2012
2	Stroke (Strokes) 02/2012 - 05/2011
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2022
1	Ventral Hernia 01/2022
1	Pancreatic Fistula (Pancreatic Fistulas) 10/2019
1	Mesenteric Ischemia 12/2018
1	Starvation 11/2017
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2017
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 10/2017
1	Hypoxia (Hypoxemia) 01/2016
1	Hepatocellular Carcinoma (Hepatoma) 01/2016

Drug/Important Bio-Agent (IBA)

12	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2023 - 11/2013
9	Saline SolutionIBA 01/2022 - 12/2010
9	CytokinesIBA 01/2020 - 11/2013
8	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 04/2018 - 09/2012
8	milk fat globuleIBA 09/2017 - 01/2011
8	Factor VIII (Coagulation Factor VIII)IBA 09/2017 - 01/2011
8	Epidermal Growth Factor (EGF)IBA 09/2017 - 01/2011
7	Interleukin-6 (Interleukin 6)IBA 12/2018 - 01/2015
7	Proteins (Proteins, Gene)FDA Link 09/2018 - 02/2012
6	Peptides (Polypeptides)IBA 01/2022 - 02/2010
6	GhrelinIBA 07/2014 - 11/2009
5	ChemokinesIBA 01/2020 - 01/2015
5	Messenger RNA (mRNA)IBA 12/2018 - 01/2015
4	Peroxidase (Myeloperoxidase)IBA 01/2022 - 04/2016
4	salicylhydroxamic acid (SHAM)IBA 04/2018 - 01/2012
4	Phosphates (Orthophosphate)IBA 04/2018 - 02/2015
4	Sirtuin 1IBA 11/2017 - 07/2014
4	SRT1720IBA 11/2017 - 07/2014
3	MicroRNAs (MicroRNA)IBA 01/2023 - 01/2020
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2022 - 01/2016
3	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2018 - 04/2015
3	Protein Kinases (Protein Kinase)IBA 09/2018 - 01/2015
3	Caspase 3 (Caspase-3)IBA 10/2017 - 04/2015
3	Adenosine Triphosphate (ATP)IBA 02/2016 - 01/2012
2	Triggering Receptor Expressed on Myeloid Cells-1IBA 01/2022 - 01/2020
2	Chemokine CXCL2IBA 01/2022 - 12/2018
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 12/2018 - 04/2015
2	InterleukinsIBA 04/2018 - 02/2016
2	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 10/2017 - 01/2016
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2017 - 02/2010
2	Glycoproteins (Glycoprotein)IBA 01/2017 - 02/2016
2	Fatty Acids (Saturated Fatty Acids)IBA 02/2016 - 01/2016
2	Fatty Acid Synthases (Fatty Acid Synthase)IBA 02/2016 - 01/2016
2	Carnitine (L-Carnitine)FDA LinkGeneric 02/2016 - 01/2012
2	Nonesterified Fatty Acids (NEFA)IBA 02/2016 - 01/2016
2	Carrier Proteins (Binding Protein)IBA 01/2016 - 09/2010
2	growth arrest-specific protein 6IBA 12/2015 - 12/2013
2	AdrenomedullinIBA 12/2010 - 09/2010
1	insulin receptor-related receptor (IRR)IBA 01/2022
1	Circulating MicroRNAIBA 01/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2018
1	Interleukin-18 (Interleukin 18)IBA 04/2018
1	Chemotactic FactorsIBA 04/2018
1	necrostatin-1IBA 04/2018
1	Oxygen (Dioxygen)IBA 11/2017
1	OsteopontinIBA 01/2017
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2017
1	Leucine (L-Leucine)FDA Link 01/2017
1	N-Formylmethionine (Formylmethionine, N)IBA 01/2017
1	Interleukin-17 (Interleukin 17)IBA 02/2016
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2016
1	OxyraseIBA 01/2016
1	CreatinineIBA 01/2016
1	Immunoglobulin G (IgG)IBA 01/2016
1	NitrogenIBA 01/2016

Therapy/Procedure

12	Ligation 01/2020 - 11/2009
12	Punctures 01/2020 - 11/2009
9	Therapeutics 12/2018 - 02/2010
6	Resuscitation 02/2016 - 02/2010
3	Intraperitoneal Injections 04/2018 - 02/2015
2	Operative Surgical Procedures 01/2022 - 09/2010
2	Transplantation 12/2015 - 03/2015
2	Critical Care (Surgical Intensive Care) 11/2013 - 01/2011
1	Length of Stay 01/2022
1	Colectomy 08/2021
1	Ostomy 08/2021
1	Pancreaticoduodenectomy 10/2019
1	Immunomodulation 01/2018
1	Intravenous Injections 01/2018
1	Intravenous Infusions 02/2016
1	Catheters 02/2016